I have to mention that Now brand Tri-Chromium also has 250 mg's of Cassia Cinnamon in each pill. It is possible that it is the Cassia Cinnamon which is helping my neurapathy or it could be a synergistic effect from the chromium and Cinnamon or also there is a chance it is all in my head, which case one could say it's a "placebo effect" ie just because you think something is helping it does. Whatever the case I'm going to keep taking my "Now" Brand Chromium with Cassia Cinnamon as long as I feel it helps my diabetic neurapathy. You may want to talk to your Doctor and give it a shot too. Shoot me an e mail if it works for you (or if it doesn't) I want to know. Have an awesome day!!! Burnie